| 4种肿瘤标志物的检测对卵巢癌的诊断价值 |
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| 引用本文： | 侯松林,向斌.4种肿瘤标志物的检测对卵巢癌的诊断价值[J].检验医学与临床,2012,9(4):418-419. |
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| 作者姓名： | 侯松林 向斌 |
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| 作者单位： | 湖南省沅陵县第二人民医院检验科,419607 |
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| 摘 要： | 目的 探讨肿癌胚抗原(CEA)、糖类抗原199(CA-199)、糖类抗原125(CA-125)和糖类抗原153(CA-153)等4种肿瘤标志物的检测对卵巢癌的诊断价值.方法 采用化学发光法检测49例卵巢癌患者、48例卵巢良性病变患者和40例健康体检者的口述4种肿瘤标志物,并探讨联合检测对诊断卵巢癌的临床价值.结果 49例卵巢癌患者血清CEA、CA-199、CA-125和CA-153阳性率明显高于卵巢良性病变组及健康对照组(均P<0.05),4项联合检测敏感性明显高于单项检测.结论 单项检测血清CEA、CA-199、CA-125和CA-153对卵巢癌的诊断有一定的临床价值,联合检测这4种标志物更具有临床意义.
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| 关 键 词： | 卵巢癌 肿瘤标志物 化学发光法 |
Clinical value of combined detection of 4 kinds of tumor markers in diagnosing ovarian cancer |
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| HOU Song-lin,XIANG Bin.Clinical value of combined detection of 4 kinds of tumor markers in diagnosing ovarian cancer[J].Laboratory Medicine and Clinic,2012,9(4):418-419. |
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| Authors: | HOU Song-lin XIANG Bin |
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| Institution: | (Department of Clinical Laboratory,Yuanlin County No.2 People＇s Hospital,Yuanlin,Hunan 419607,China) |
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| Abstract: | Objective To investigate the clinical significance of serum levels of CEA,CA19-9,CA-125 and CA-153 in diagnosing ovarian cancer.Methods The levels of CEA,CA19-9,CA-125 and CA-153 in 49 patients with ovarian cancer,48 patients with benign ovarian tumor and 40 healthy controls were measured by chemistry luminescence immunoassay method.Results The serum levels of CEA,CA19-9,CA-125 and CA-153 in the ovarian cancer group were significantly higher than those in the benign ovarian tumor group and healthy controls.The sensitivity of combination detection of the four markers was higher than that of single item.Conclusion Detection of CEA,CA19-9,CA-125 and CA-153 has certain diagnostic valus to ovarian cancer.The clinical value can be improved by combined detection of the four markers. |
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| Keywords: | ovarian cancer tumor marker chemistry luminescence immunoassay method |
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