C-反应蛋白在关节置换术后变化的动态观察

目的通过术前、术后常规监测C-反应蛋白(CRP)指标,了解关节置换患者在无感染情况时正常动态变化曲线。方法选择初次关节置换患者98例,于术前及术后第1、3、7、14天各采集清晨同一时间段空腹静脉血,测定WBC、ESR、CRP,并详细记录患者性别、年龄、疾病类型、手术方式、是否输血等可能影响数值变化的相关因素。用SPSS 13.0软件处理分析结果并用Excel绘制线图。结果 CRP变化曲线的轮廓基本一致,于术后出现先迅速升高,至术后第3天达到顶峰,至术后2周平均值可降至稍高于正常。结论根据CRP正常动态变化曲线,对发现、判断关节置换患者早期可能出现的感染有重要的意义。

Continuous monitoring of serum C-reactive protein after joint replacement

Objective To study the C-reactive protein(CRP) expression by routinely monitoring variation of serum CRP before and after joint replacement without infection and to know the normal dynamic change of the CRP.Methods 98 cases with joint replacement were recruited.White blood cell(WBC),erythrocyte sedimentation rate(ESR),and CRP were monitored before operations and in the 1st,3rd,7th,and 14th day after operations.The possible correlation factors such as sex,age,disease type,operation type and blood transfusion were analyzed statistically and drew linear chart with Excel.Results The level of CRP after operation in patients without infection increased after surgery,to the peak in 3 days,and then descended to normal level in 2 weeks.Conclusions It is important to discover and judge early infection after joint replacement with the development change of the CRP.