2011—2012年新疆维吾尔自治区人民医院药疹患者临床分析及药学监护的建议

目的 了解住院患者药疹的情况和重症药疹的皮疹特点,并对此提出药学监护分析建议.方法 回顾性分析2011年-2012年新疆维吾尔自治区人民医院收治确诊药疹的患者169例,了解住院患者药疹的情况和重症药疹的皮疹特点,并对此提出药学监护分析建议.结果 本次调查药疹致敏药物主要构成为抗菌药物类(占45.56％)、中药类(占24.85％)、解热镇痛类药物(占15.98％)；药疹疹型主要构成为荨麻疹型(43.79％)、发疹型(19.53％)、多形红斑型(13.02％).结论 抗菌药物类和中药类是药疹的主要致敏药物,建议临床医务人员应详细询问患者用药史,发生皮疹时应及时停用可疑致敏药物,并加强对皮疹的药学监护工作.

Clinical analysis and pharmaceutical care of inpatients in People's Hospital of Xinjiang Uygur Autonomous Region from 2011 to 2012

Objective To investigate the clinical feature of inpatients with drug eruption and explore the pharmaceutical care of those inpatients. Methods A retrospective analysis was carried out on the clinical data of 169 drug eruption cases from 2011 to 2012. Results The composition of causative drugs was antimicrobial drugs (45.56%), Chinese materia medica (CMM, 24.85%), and antipyretic analgesic (15.98%). The composition of clinical manifestation was urticaria type (43.79%), exanthesis type (19.53%), and rash erythematous type (13.02%). Conclusion The major involved drugs inpatients with drug eruption are antimicrobial drugs and CMM. It is necessary for the medical staff to know the drug-used history of inpatients and to stop using questionable allergize drugs promptly, at the same time, to receive the pharmaceutical care provided by clinical pharmacists.