| 王不留行防治去势大鼠骨质疏松症的实验研究 |
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| 引用本文： | 伍杨,邓明会,陈显兵.王不留行防治去势大鼠骨质疏松症的实验研究[J].四川中医,2010(5):58-59. |
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| 作者姓名： | 伍杨 邓明会 陈显兵 |
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| 作者单位： | 湖北民族学院医学院; |
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| 基金项目： | 湖北省自然科学基金项目(项目编号:2006ABA034) |
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| 摘 要： | 目的：探讨王不留行防治去势大鼠骨质疏松症的作用。方法：运用切除大鼠卵巢的方法建立大鼠去势骨质疏松模型,分假手术组、模型组（去除卵巢组）、E2组（去除卵巢＋尼尔雌醇）、药物组（去除卵巢＋王不留行）。术后3个月,测血清IL-1、IL-6、TNF-α含量。结果：王不留行可明显降低血清IL-1、IL-6、TNF-α含量（P〈0.01）。结论：王不留行对去势大鼠骨质疏松症有明显的防治作用,这种作用可能与王不留行的雌激素活性,降低骨的转移率和增加骨形成有关。
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| 关 键 词： | 王不留行 骨质疏松症 实验研究 |
Experimental Study of Preventing Ovariectomized Rats from Osteoporosis by Vaccaria segetalis |
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| Wu Yang Deng Minghui Chen Xianbing Medical School of Hubei Institute for Nationalities.Experimental Study of Preventing Ovariectomized Rats from Osteoporosis by Vaccaria segetalis[J].Journal of Sichuan of Traditional Medicine,2010(5):58-59. |
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| Authors: | Wu Yang Deng Minghui Chen Xianbing Medical School of Hubei Institute for Nationalities |
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| Institution: | Wu Yang Deng Minghui Chen Xianbing Medical School of Hubei Institute for Nationalities(Enshi Hubei 445000,China) |
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| Abstract: | Objective：To study the effect of Vaccaria segetalis on the prevention of osteoporosis in ovariectomized rats.Methods：Osteoporosis model was established by means of ovariectomy.which were divided into sham operation group,ovariectomized group,ovariectomized-nilestriol group and ovariectomized-Vaccaria segetalis group.The test of IL-1、IL-6、TNF-α in the serum were measured.Results：Vaccaria segetalis can decrease the concentration of IL-1、IL-6、TNF-α（P〈0.01）.Conclusions：Vaccaria segetalis has antiosteoporotic effects on ovariectomized rats by inhibiting the bone turnover and improves bone forming by active of female hormone. |
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| Keywords: | vaccaria segetalis Osteoporosis experimental research |
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