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Effect of dental treatment before cardiac valve surgery: Systematic review and meta-analysis
Authors:Peter B. Lockhart  Hillary R. DeLong  Ruth D. Lipman  Elliot Abt  Larry M. Baddour  Monica Colvin  Craig S. Miller  Thomas Sollecito  Kelly O’Brien  Cameron G. Estrich  Marcelo W.B. Araujo  Alonso Carrasco-Labra
Abstract:BackgroundThe purpose of this systematic review was to determine the potential effect of dental treatment before cardiac valve surgery (CVS) or left ventricular assist device (LVAD) implantation on morbidity and mortality.Types of Studies ReviewedThe authors included relevant studies from MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials, including randomized controlled trials and cohort studies, published from 1998 through 2019 and involving adults who received dental treatment before CVS or LVAD implantation. The authors assessed bias by using the Newcastle-Ottawa Quality Assessment Scale and evidence certainty by using the Grading of Recommendations Assessment, Development and Evaluation approach. The authors used a meta-analysis with a random-effects model to estimate dichotomous and continuous outcomes, expressed as relative risk (RR) and weighted mean difference.ResultsSix studies met the inclusion criteria for CVS but none for LVAD implantation. Very low certainty in the evidence suggested uncertainty as to whether health outcomes for patients undergoing dental treatment before CVS differed from those who did not. Postsurgical outcomes included all-cause mortality (RR, 1.00; 95% confidence interval [CI], 0.53 to 1.91), infective endocarditis (RR, 1.30; 95% CI, 0.51 to 3.35), postsurgical infection (RR, 1.01; 95% CI, 0.76 to 1.33), and length of stay in the hospital (weighted mean difference, 2.9; 95% CI, ?2.3 to 8.1).Conclusions and Practical ImplicationsFrom the available evidence, it is unclear whether postoperative outcomes differ in patients receiving dental treatment before CVS compared with outcomes in those who do not. Dentists and medical care professionals should collaborate on an appropriate course of action for each patient, weighing any potentially relevant care considerations.
Keywords:Address correspondence to Ms. DeLong.  Cardiac  pretreatment  medically complex  presurgical  dental clearance  ADA  American Dental Association  CVS  Cardiac valve surgery  dm_su  Disease management- surgery subheading  exp  Explode  GRADE  Grading of Recommendations Assessment, Development and Evaluation  IE  Infective endocarditis  lnk  Link  LOS  Length of stay  LVAD  Left ventricular assist device  MeSH  Medical Subject Headings  NA  Not applicable  NR  Not reported  py  Publication year  RCT  Randomized controlled trial  tiab  Title abstract  ti,ab,kw  Title, abstract, key word
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