Eficacia del corticoide intratimpánico como tratamiento de rescate en sordera súbita neurosensorial idiopática |
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Authors: | Elizabeth Amarillo Mónica Hernando Gustavo Eisenberg Mónica Granda Guillermo Plaza |
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Institution: | 1. Servicio de Otorrinolaringología, Complejo Hospitalario Mancha Centro, Alcázar de San Juan, Ciudad Real, España;2. Servicio de Otorrinolaringología, Hospital Universitario de Fuenlabrada, Universidad Rey Juan Carlos, Madrid, España;3. Facultad de Medicina, Universidad Rey Juan Carlos, Madrid, España |
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Abstract: | IntroductionIdiopathic sudden sensorineural hearing loss (ISSHL) is defined as an abrupt hearing loss of at least 30 dB of unknown cause. The hearing response obtained after intratympanic steroid injection as a salvage treatment after a prior failure of initial systemic steroid treatment was analysed.Material and methodAn observational study was performed on 125 cases of ISSHL who were diagnosed from 2006 to 2014. Sixteen achieved complete recovery after one week according to Siegel's criteria. The remaining 109 cases were analysed in two groups: one that received intratympanic corticosteroid salvage therapy (treatment group) and one that did not (control group). The recovery was analysed after 6 months and 2 years of follow-up.ResultsThe difference between each group at baseline were not statistically significant. After systemic treatment for 7 days, PTA in the control group was 53.13 dB and 66.11 dB in the treatment group (P < .01). After 6 months, the mean PTA improvement was 10.84 dB in the treatment group, and 1.13 dB in the control group, a significant difference (P < .0001). Only 10 cases achieved full hearing recovery after intratympanic corticosteroid salvage therapy, none of the patients did so in the control group.ConclusionIntratympanic corticosteroid rescue for ISSHL acheived hearing improvement for the cases with failure of initial systemic corticosteroid treatment. However, this treatment did not provide complete hearing recovery according to Siegel's criteria in most cases. |
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Keywords: | Autor para correspondencia Sordera súbita Sordera súbita idiopática Corticoide sistémico Rescate intratimpánico Recuperación Mejoría Sudden deafness Sensorineural hearing loss Systemic therapy Intratympanic steroid Recovery Response |
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