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Clinical and Socioeconomic Predictors of Heart Failure Readmissions: A Review of Contemporary Literature
Authors:Amanda Su,Subhi J. Al&#x  Aref,Ashley N. Beecy,James K. Min,Maria G. Karas
Affiliation:1. Dalio Institute of Cardiovascular Imaging, NewYork–Presbyterian Hospital, New York, NY;2. Department of Medicine, Weill Cornell Medicine, New York, NY;3. Department of Radiology, Weill Cornell Medicine, New York, NY;4. Department of Cardiology, Weill Cornell Medicine, New York, NY
Abstract:Heart failure represents a clinical syndrome that results from a constellation of disease processes affecting myocardial function. Although recent studies have suggested a declining or stable incidence of heart failure, patients with heart failure continue to have high hospitalization and readmission rates, resulting in a substantial economic and public health burden. We searched PubMed and Google Scholar to identify published literature from 1998 through 2018 using the following keywords: heart failure, readmissions, predictors, prediction models, and interventions. Cited references were also used to identify relevant literature. Developments in the diagnosis and management of patients with heart failure have improved hospitalization and readmission rates in the past few decades. However, heart failure remains the most common cause of hospitalization in persons older than 65 years. As a result, given the enormous clinical and financial burden associated with heart failure readmissions on health care, there has been growing interest in the investigation of mechanisms aimed at improving outcomes and curtailing associated costs of care. Herein, we review the current literature on clinical and socioeconomic predictors of heart failure readmissions, briefly discussing limitations of existing strategies and providing an overview of current technology aimed at reducing hospitalizations.
Keywords:ACC  American College of Cardiology  ACEI  angiotensin-converting enzyme inhibitor  AHA  American Heart Association  ARB  angiotensin receptor blocker  BNP  B-type natriuretic peptide  CMS  Centers for Medicare and Medicaid Services  COPD  chronic obstructive pulmonary disease  FDA  Food and Drug Administration  Gal-3  galectin-3  HF  heart failure  HFpEF  heart failure with preserved ejection fraction  HFrEF  heart failure with reduced ejection fraction  HR  hazard rate  HRRP  Hospital Readmissions Reduction Program  ICD  implantable cardioverter-defibrillator  LV  left ventricle  nINC  neighborhood median household income  NT-proBNP  N-terminal pro-B–type natriuretic peptide  NYHA  New York Heart Association  OPTIMIZE-HF  Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure
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