Holmium Nanoparticles: Preparation and <Emphasis Type="Italic">In Vitro</Emphasis> Characterization of a New Device for Radioablation of Solid Malignancies期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Holmium Nanoparticles: Preparation and In Vitro Characterization of a New Device for Radioablation of Solid Malignancies

Authors:	Wouter Bult Rosanne Varkevisser Fouad Soulimani Peter R. Seevinck Hendrik de Leeuw Chris J. G. Bakker Peter R. Luijten Alfred D. van het Schip Wim E. Hennink J. Frank W. Nijsen

Affiliation:	(1) Department of Radiology and Nuclear Medicine, Imaging Division, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands;(2) Department of Pharmaceutics Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, P.O. Box 80082, 3508 TB Utrecht, The Netherlands;(3) Inorganic Chemistry and Catalysis Group, Department of Chemistry Faculty of Science, Utrecht University, P.O. Box 80083, 3508 TB Utrecht, The Netherlands;(4) Imaging Sciences Institute, Imaging Division, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands;(5) Present address: Department of Medical Physiology, Division Heart and Lungs, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands

Abstract:	Purpose The present study introduces the preparation and in vitro characterization of a nanoparticle device comprising holmium acetylacetonate for radioablation of unresectable solid malignancies.

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