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Oxytocics for the prevention of post-partum haemorrhages A review |
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| Authors: | P. W. J. Van Dongen J. Van Roosmalen C. N. De Boer J. Van Rooij |
| Affiliation: | (1) Department of Obstetrics and Gynaecology, University Hospital Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, the Netherlands;(2) Department of Obstetrics and Gynaecology, University Hospital Leiden, P.O. Box 9600, 2300 RC Leiden, the Netherlands;(3) Department of Obstetrics and Gynaecology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, the Netherlands |
| Abstract: | Secale alkaloids, oxytocin and prostaglandins are used to prevent post-partum haemorrhage (post-partum haemorrhage defined as blood loss  500 ml). Any oxytocic drug administered in the third stage of labour reduces the blood loss with approximately 40% and hence the incidence of post-partum haemorrhage from 10 to 6%. Therefore, routine active management of the third stage with an oxytocic drug is strongly advocated. Because of the fewest side-effects oxytocin is regarded as the best drug available at this moment. |
| Keywords: | Drug stability Ergometrine Hemorrhage, postpartum/prevention and control Oxytocin Prostaglandins Risk factors Side effects |
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