热性惊厥患儿血清胰岛素样生长因子-1水平的变化 |
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引用本文: | 黄伟,于丹军,苏颖,邱锐琴,顾艳红,董蕾. 热性惊厥患儿血清胰岛素样生长因子-1水平的变化[J]. 中国妇幼保健, 2009, 24(16) |
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作者姓名: | 黄伟 于丹军 苏颖 邱锐琴 顾艳红 董蕾 |
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作者单位: | 河北省秦皇岛市第一医院,066000 |
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基金项目: | 河北省秦皇岛市科学技术研究与发展指导计划项目 |
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摘 要: | 目的:探讨热性惊厥患儿的血清胰岛素样生长因子-1(IGF-1)水平和临床意义。方法:用放免法检测10例热性惊厥患儿和对照组20例健康儿童的血清IGF-1水平。结果:热性惊厥患儿的血清IGF-1水平显著高于对照组(P<0.01)。结论:热性惊厥患儿急性期血清IGF-1升高,证明存在中枢神经细胞损伤。
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关 键 词: | 胰岛素样生长因子-1 热性惊厥 儿童 中枢神经细胞损伤 |
Changes of insulin like growth factor - 1 level in serum in children with febrile convulsion |
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Abstract: | Objective:To explore the level of insulin-like growth factor-1(IGF-1)in serum and its significance in children with febrile convulsion.Methods:The levels of IGF-1 in serum from 20 children with febrile convulsion and 20 healthy children were detected by radioimmunoassay.Results:The level of IGF-1 in serum of children with febrile convulsion was higher than that of healthy children(P<0.01).Conclusion:The high level of IGF-1 in serum in acute stage of febrile convulsion indicates the damage of nerve cells of central nervous system in children. |
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Keywords: | Insulin like growth factor-1 Febrile convulsion Children Damage of nerve cells of central nervous system |
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