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热性惊厥患儿血清胰岛素样生长因子-1水平的变化
引用本文:黄伟,于丹军,苏颖,邱锐琴,顾艳红,董蕾. 热性惊厥患儿血清胰岛素样生长因子-1水平的变化[J]. 中国妇幼保健, 2009, 24(16)
作者姓名:黄伟  于丹军  苏颖  邱锐琴  顾艳红  董蕾
作者单位:河北省秦皇岛市第一医院,066000
基金项目:河北省秦皇岛市科学技术研究与发展指导计划项目
摘    要:目的:探讨热性惊厥患儿的血清胰岛素样生长因子-1(IGF-1)水平和临床意义。方法:用放免法检测10例热性惊厥患儿和对照组20例健康儿童的血清IGF-1水平。结果:热性惊厥患儿的血清IGF-1水平显著高于对照组(P<0.01)。结论:热性惊厥患儿急性期血清IGF-1升高,证明存在中枢神经细胞损伤。

关 键 词:胰岛素样生长因子-1  热性惊厥  儿童  中枢神经细胞损伤

Changes of insulin like growth factor - 1 level in serum in children with febrile convulsion
Abstract:Objective:To explore the level of insulin-like growth factor-1(IGF-1)in serum and its significance in children with febrile convulsion.Methods:The levels of IGF-1 in serum from 20 children with febrile convulsion and 20 healthy children were detected by radioimmunoassay.Results:The level of IGF-1 in serum of children with febrile convulsion was higher than that of healthy children(P<0.01).Conclusion:The high level of IGF-1 in serum in acute stage of febrile convulsion indicates the damage of nerve cells of central nervous system in children.
Keywords:Insulin like growth factor-1  Febrile convulsion  Children  Damage of nerve cells of central nervous system
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