| 合成前列腺素E_1的中间体-γ亚麻酸甲酯的制备 |
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| 引用本文： | 高雅琴,李霞冰,朱廷儒. 合成前列腺素E_1的中间体-γ亚麻酸甲酯的制备[J]. 沈阳药科大学学报, 1985, 0(2) |
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| 作者姓名： | 高雅琴 李霞冰 朱廷儒 |
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| 作者单位： | 中国科学院林业土壤研究所，中国科学院林业土壤研究所，中国科学院林业土壤研究所 |
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| 摘 要： | 以r-亚麻酸甲酯为原料可合成二高-r-亚麻酸,再经生物合成得前列腺素E_1。本文报道了由月见草(Oenothera biennis)种子油制备 r-亚麻酸甲酯的方法。所得产品为无色或微带黄色的油状液体,含有 r-亚麻酸60%(GLC)以上。按月见草油计算,总收率约3%。
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| 关 键 词： | 月见草 r-亚麻酸 r-亚麻酸甲酯 二高-r 亚麻酸 前列腺素 E_1 |
PREPARATION OF THE INTERMEDIATE MATERIAL FOR SYNTHESIZING PROSTGLANDIN E_1 FROM PLANT RESOURCES—METHYL γ-LINOLENATE |
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| Gao Yaqin Li Xiabing Zhu Tingru Institute of Forestry and Pedology,Academia Sinica,Shenyang. PREPARATION OF THE INTERMEDIATE MATERIAL FOR SYNTHESIZING PROSTGLANDIN E_1 FROM PLANT RESOURCES—METHYL γ-LINOLENATE[J]. Journal of Shenyang Pharmaceutical University, 1985, 0(2) |
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| Authors: | Gao Yaqin Li Xiabing Zhu Tingru Institute of Forestry Pedology Academia Sinica Shenyang |
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| Abstract: | Dihomo-γ-Linolenic acid was obtained chemically using methyl γ-linolenate as starting material.It could then be converted into prostglandin E_1 through bio- synthesis.In this paper,a modern method for preparing methyl γ-linolenate from the seed oil of Oenothera biennis was reported.The product obtained was a col- ourless or light yellowish oil.The content of γ-linolenic acid was higher than 60%(GLC).The total yield was about 3% caculated on the weight of the seed oil. |
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| Keywords: | Oenothera biennis γ-Linolenic acid Methyl γ-1inolenate Dihomo-γ-linolenic acid Prostaglandin E |
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