性心肌梗死患者血浆脑钠肽含量的变化

目的：研究急性心肌梗死（AMI）患者与不稳定型心绞痛（UAP）患者血浆脑钠肽（BNP）含量的变化和临床意义。方法i选择我院60例AMI患者（AMI组）和58例UAP患者（UAP组），检测两组入院时及入院2周后BNP水平，并进行比较分析。结果：入院时，AMI患者BNP水平明显高于UAP组（1084．7±385．3）pg／m1比（72．57±3．35）pg／ml，P〈0．01]；入院2周后，AMI患者BNP水平显著下降（256．4±134．5）pg／m1]，P〈0．01，但仍显著高于UAP组（65．29±3．62）pg／ml]，P〈0．01。结论：血浆脑钠肽水平可反映急性心肌梗死患者心功能恢复的程度，对改善心功能治疗有指导意义。

Changes of plasma brain natriuretic peptide level in patients with acute myocardial infarction

Objective： To study change of plasma level of brain natriuretic peptide （BNP） in patients with acute myo- cardial infarction （AMI） and patients with unstable angina pectoris （UAP） and its clinical significance. Methods.. A total of 60 AMI patients （AMI group） and 58 UAP patients （UAP group） from our hospital were enrolled. BNP level was measured in two groups at admission and two weeks after admission, and then compared and analyzed. Resuits： At admission, BNP level of AMI group was significantly higher than that of UAP group （1084.7±385.3） pg/ ml vs. （72.57±3.35） pg/ml, P〈0. 01]. two weeks after admission, BNP level of AMI group （256. 4±134.5） pg/ ml] was significantly decreased （P〈0.01）, but it was still significantly higher than that of UAP group （65.29 ± 3.62） pg/ml], P〈0.01. Conclusion： Level of brain natriuretic peptide in patients with acute myocardial infarction can reflect the recovery degree of cardiac function, and its detection contributes to guide cardiac function therapy.