| 抗眼底新生血管药物的研究进展 |
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| 引用本文： | 姚燕鸿,张琼,王玲.抗眼底新生血管药物的研究进展[J].国际眼科杂志,2010,10(5):901-904. |
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| 作者姓名： | 姚燕鸿 张琼 王玲 |
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| 作者单位： | 上海交通大学医学院附属瑞金医院眼科,中国上海市,200025 |
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| 基金项目： | 中国上海市科委基础重点项目，中国上海市重点学科建设资助项目 |
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| 摘 要： | 视网膜和脉络膜新生血管可引发玻璃体出血、视网膜下出血、牵引性视网膜脱离等,从而危害患眼视力。这类病变常见于老年性黄斑变性(age related macular degeneration,AMD)、糖尿病视网膜病变(diabetic retinopathy,DR)、视网膜静脉阻塞(retinal vein occlusions,RVO)、早产儿视网膜病变(retinopathy of prematurity,ROP)等眼底病。当前,药物治疗新生血管(neovscularization,NV)主要是针对NV生成的不同阶段抑制其生长。本文综述了目前已用于临床及正在进行临床试验的治疗眼底新生血管的药物。
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| 关 键 词： | 新生血管形成 抗新生血管药物 视网膜 脉络膜 |
Recent advance of the study on the antineovascular drugs for fundus diseases |
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| Yan-Hong Yao,Qiong Zhang and Ling Wang.Recent advance of the study on the antineovascular drugs for fundus diseases[J].International Journal of Ophthalmology,2010,10(5):901-904. |
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| Authors: | Yan-Hong Yao Qiong Zhang and Ling Wang |
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| Institution: | Yan-Hong Yao,Qiong Zhang,Ling WangDepartment of Ophthalmology,Ruijin Hospital of Shanghai Jiaotong University School of Medicine,Shanghai 200025,China |
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| Abstract: | ·Retina and choroid neovascularization(NV)may induce vitreous hemorrhage,subretinal hemorrhage and tractional retinal detachment and usually result in poor vision.It is often seen in the eyes with age-related macular degeneration(AMD),diabetic retinopathy(DR),retinal vein occlusions(RVO)and retinopathy of prematurity(ROP).At present,drugs of NV mainly target the different phases of the angiogenesis and suppress its growth.We discusse the present anti-neovascular drugs which are used on clinic or under the clinicaltrial.· |
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| Keywords: | neovascularization anti-neovascular drugs retina choroid |
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