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基于膜分离技术富集纯化肉苁蓉苯乙醇苷的研究
引用本文:胡君萍,闫瑶,杨建华.基于膜分离技术富集纯化肉苁蓉苯乙醇苷的研究[J].中药新药与临床药理,2012,23(4):480-483.
作者姓名:胡君萍  闫瑶  杨建华
作者单位:1. 新疆医科大学药学院,乌鲁木齐,830011
2. 新疆医科大学药学院,乌鲁木齐830011;新疆医科大学附属肿瘤医院,乌鲁木齐830011
基金项目:国家自然科学基金,乌鲁木齐市科技应用开发计划
摘    要:目的探讨膜分离技术提取分离肉苁蓉有效成分的应用价值。方法肉苁蓉80%乙醇提取,以水溶解,经不同截留分子量超滤膜超滤,再经纳滤膜处理,用高效液相色谱法检测毛蕊花糖苷和松果菊苷的含量。结果不同截留分子量超滤膜处理,产品的出膏率和目标成分的含量存在明显差异。结论该方法可显著降低生产成本,清洁安全,方法可行。

关 键 词:膜分离技术  肉苁蓉  毛蕊花糖苷  松果菊苷

Membrane Separation Technology of Phenylethanoid Glycosides in Herba Cistanches
HU Junping , YAN Yao , YANG Jianhua.Membrane Separation Technology of Phenylethanoid Glycosides in Herba Cistanches[J].Traditional Chinese Drug Research & Clinical Pharmacology,2012,23(4):480-483.
Authors:HU Junping  YAN Yao  YANG Jianhua
Institution:1,(21. College of Pharmacy,Xinjiang Medical University,Urumqi 830011, China;2. Affiliated Tumor Hospital,Xinjiang Medical University,Urumqi 830011,China)
Abstract:Objective To investigate the practical value of membrane separation technology for the separation the effective ingredients in Herba Cistanches.Methods Herba Cistanches was extracted with 80 % of ethanol,dissolved in water,treated with different molecular weight cutoff(MWCO) ultrafiltration membrane,and then filtered with nanofiltration membrane.The content of verbascoside and echinacoside were detected by HPLC.Results The cream yield of the target and the content of verbascoside and echinacoside varied in different MWCO ultrafiltration membrane treatment.Conclusion This method can significantly reduce production costs.It is clean,safe and feasible.
Keywords:Membrane separation technology  Herba Cistanches  Verbascoside  Echinacoside
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