| 正交试验法优化茵栀黄颗粒提取工艺 |
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| 引用本文： | 丁红仙.正交试验法优化茵栀黄颗粒提取工艺[J].浙江中医药大学学报,2008,32(3):394-396. |
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| 作者姓名： | 丁红仙 |
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| 作者单位： | 浙江省义乌市中医院,义乌,322000 |
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| 摘 要： | 目的]优化茵栀黄颗粒的提取工艺。方法]以干膏得率和绿原酸提取率为考核指标,采用正交设计法对茵栀黄颗粒水提取工艺进行考察。结果]茵栀黄颗粒最佳提取工艺的方案为A2B1C2,即加水量为8倍,提取2次,每次1h。结论]优选的提取工艺科学合理,适于大规模生产。
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| 关 键 词： | 茵栀黄颗粒 高效液相色谱法 正交试验 提取工艺 |
| 文章编号： | 1005-5509(2008)03-0394-03 |
| 修稿时间： | 2008年3月15日 |
Optimization of Extraction Procession of Yinzhihuang Granules with Orthogonal Design |
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| Ding Hongxian.Optimization of Extraction Procession of Yinzhihuang Granules with Orthogonal Design[J].Journal of Zhejiang University of Traditional Chinese Medicine,2008,32(3):394-396. |
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| Authors: | Ding Hongxian |
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| Abstract: | Objective]To optimize extracting procession of Yinzhihuang granules.Methods]The extraction procession was studied by orthogonal design with dry extract yield and total flavonoids as the detective marker.Results] The optimum extraction condition is A2B1C2,which is added 8 fold of water,and decocted for 2 times,1 hour at every time.Conclusion] The optimized water-decocting condition is reasonable and scientific,and it could be used in future large-scaled preparation of Yinzhihuang granules. |
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| Keywords: | Yinzhihuang granules HPLC orthogonal design extraction technical |
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