836例成都市育龄男性精子质量分析

目的了解成都市正常育龄男性精子质量状况,促进优生优育工作。方法对836例育龄男性完整精液标本进行分析,并根据年龄分为〈25岁、25-29岁、30-35岁、36-39岁、〉40岁5组,分析比较各组精液参数。结果836名育龄男性精液量（2.85±0.92）ml,pH值（7.46±0.16）,精子密度（77.15±53.88）×10^6/ml,精子活率（67.36±18.41）%,a级精子（30.08±12.90）%,a＋b级精子（49.81±14.92）%。其中正常组515例（61.60%）,异常组321例（38.40%）。异常组中,225例精子活力异常（70.09%）,215例精子活率异常（66.98%）,86例精液量异常（26.79%）,54例精子密度异常（16.82%）,8例pH值异常（2.49%）,7例无精子（2.18%）。结论我市育龄男性精子质量基本处于WHO规定的标准内,但精子活力下降比例较高。在不同年龄分组研究中25-29岁年龄组精子质量好于其他年龄组,随着年龄增加精子质量呈下降趋势,在育前保健中应重点针对精子活力下降状况,开展保健服务,以利于优生优育。

Investigation on the sperm quality of 836 normal reproductive males in the Chengdu city

Objective To investigate the sperm quality of normal reproductive men in Chengdu area, and promote the progrm or improve birth outcome and child development in our district. Methods Whole the 836 normal reproductive men who were divided into five groups due to their age：younger than 25 years old, between 25 and 29 years old,30 and 35 years old,36 and 39 years old and older than 40 years old. Results Among the 836 normal reproductive males, the semen volume was （2. 85 ± 0. 92） ml, pH value was （ 7.46 ± 0. 16 ）, the sperm concentration was （77. 15 ± 53. 88 ） × 10^6/ml, the sperm viability rate was （67.36± 18.41 ） %, grade A sperm was （30. 08 ± 12. 90） % and the grade A and B sperm was （49. 81 ± 14. 92） %. The samples with normal sperm quality accounted for 61.60% （515/836） in contrast with abnormal 38.40% （321/836）. Among the abnormal samples, there were 225 （70. 09% ） with abnormal motility,215 （66. 98 % ） with abnormal viability,86 （26. 79% ） with abnormal semen volume,54（16. 82% ）with abnormal concentration,8 （2.49%） with abnormal pH value and 7（2. 18% ） samples which without sperm. Conclusion The semen quality of the normal reproductive male population in Chengdu area is up to the WHO standard, but the abnormal sperm motility has a highly proportion. In the whole normal reproductive males, who that between 25 and 29 years old had a better semen quality than the others, but the semen quality had a trend to be worse when the men become older and older. So,we should spread out the health care service mainly against sperm viability decreasing in the health care before marriage, and suggest deploying the routine examination of semen, then we can promote the work of improving birth outcome and child development.