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香椿保健茶毒性的初步研究
引用本文:程东,都国山,韩晓英,张天亮.香椿保健茶毒性的初步研究[J].中国预防医学杂志,2007,8(5):576-579.
作者姓名:程东  都国山  韩晓英  张天亮
作者单位:1. 山东省疾病预防控制中心,济南,250014
2. 山东省安丘市柘山中心卫生院
3. 山东师范大学生命科学学院
摘    要:目的研究香椿保健茶的毒性。方法小鼠急性毒性实验、Ames实验、小鼠骨髓嗜多染红细胞微核实验、小鼠精子畸形实验、大鼠30d喂养实验。结果香椿保健茶属无毒物质;Ames实验、微核实验和精子畸形实验结果均为阴性;大鼠30d喂养实验结果显示该样本30d喂养对大鼠各项观察指标未见毒性作用。结论在本次实验条件下,香椿保健茶为无毒物质,未显示有遗传毒性和亚急性毒性作用。

关 键 词:香椿保健茶  急性毒性实验  遗传毒性实验  大鼠30d喂养实验
修稿时间:2006-12-25

Study of Toxicity of Toona Sinensis Health Care Tea
CHENG Dong , DU Guo-shan, HAN Xiao-ying, et al.Study of Toxicity of Toona Sinensis Health Care Tea[J].China Preventive Medicine,2007,8(5):576-579.
Authors:CHENG Dong  DU Guo-shan  HAN Xiao-ying  
Institution:Department of Toxicology, Shandong Center for Disease Control and Prevention, Jinan 250014, China
Abstract:Objective To study the toxicity of the toona sinensis health care tea.Methods Acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice,sperm shape abnormality test of mice,thirty day feeding study were.Results The toona sinensis health care tea was a substance with no toxicity.The results of genetic toxicity tests,including Ames test,micronucleus test and sperm shape abnormality test were all negative.The result of thirty day feeding study was also negative.Conclusions The toona sinensis health care tea was a substance with no acute toxicity and had no genetic toxicity and had no subacute toxicity in this test.
Keywords:Toona sinensis health care tea  Acute toxicity test  Genetic toxicity  Thirty day feeding study
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