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Radically resected epithelioid angiosarcoma that originated in the mediastinum
Authors:Shinya Tane  Yugo Tanaka  Syunsuke Tauchi  Kazuya Uchino  Reiko Nakai  Masahiro Yoshimura
Affiliation:(1) Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1–1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807–8555, Japan;(2) Department of Pathology, NTT MC Kanto Medical Center, Tokyo, Japan;(3) Department of Radiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan;(4) Division of Orthopedic Surgery, Kokura National Hospital, Kitakyushu, Japan;
Abstract:Angiosarcoma is a rare neoplasm, accounting for only 1%–2% of all sarcomas. It occurs most frequently in the skin and soft tissue and rarely in the thoracic region. To our knowledge, a mediastinal angiosarcoma is extremely rare. We report on the surgical resection of a rare case of giant epithelioid angiosarcoma originating in the anterior mediastinum, followed by six courses of adjuvant chemotherapy (doxorubicin + ifosfamide). The patient is alive and asymptomatic 1 year after surgery. As the prognosis for unresectable cases is generally dismal, surgical resection and adjuvant therapy can be an option for mediastinal angiosarcoma.
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