| 妊娠与甲状腺功能减退症 |
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| 引用本文： | 张晓兰.妊娠与甲状腺功能减退症[J].国外医学：妇产科学分册,2009,36(1):30-33. |
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| 作者姓名： | 张晓兰 |
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| 作者单位： | 东南大学医学院附属江阴医院内分泌科;南京医科大学第一附属医院内分泌科; |
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| 基金项目： | 江苏省社会发展基金(BS2004039) |
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| 摘 要： | 妊娠期间甲状腺激素的合成、分泌、代谢、调节及甲状腺免疫环境均发生相应的改变，而甲状腺功能障碍亦可从月经、排卵、受孕、胚胎分化、分娩等各阶段影响妊娠结局。已发现，即使是亚临床甲状腺功能减退症，或甲状腺功能正常的自身免疫性甲状腺疾病，对妊娠亦产生不良影响。因此妊娠合并甲状腺功能减退症的早期诊断尤为重要。目前促甲状腺激素（TSH）仍作为诊断妊娠期甲状腺疾病首选的指标。推荐将2．5mU／L作为妊娠早期母体血清TSH水平的保守上限值。有自身免疫性甲状腺疾病者在妊娠期发生甲状腺功能不足的几率较高，需密切监测。
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| 关 键 词： | 甲状腺功能减退症 自身免疫性甲状腺疾病 自然妊娠 辅助生殖技术 流产 |
Pregnancy and Hypothyroidism |
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| ZHANG Xiao-lan,DUAN Yu.Pregnancy and Hypothyroidism[J].Foreign Medical Sciences(Obstet Gynecol Fascicle),2009,36(1):30-33. |
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| Authors: | ZHANG Xiao-lan DUAN Yu |
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| Institution: | ZHANG Xiao-lan;DUAN Yu |
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| Abstract: | The synthesis,secretion,metabolism and regulation of thyroid hormones during pregnancy all change with gestational age as well as thyroid immunity.At the same time,dysfunctions of the thyroid can influence menstruation,ovulation,fertilization,embryonic differentiation and delivery,thus affecting the pregnancy outcome.In the present review,we discuss the various effects of hypothyroidism during pregnancy.Of note,even subclinical hypothyroidism or autoimmune thyroid disease with euthyroidism can adversely imp... |
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| Keywords: | Hypothyroidism Autoimmune thyroid disease Natural pregnancy Artificial assisted repro-duction technique Miscarriage |
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