右心室流出道间隔部和心尖部起搏术后12个月血NT-proBNP水平观察

目的 比较右心室流出道间隔部起搏和右心室心尖部起搏对术后12个月患者心脏收缩功能的影响。方法 观察我院100例病窦综合征并首次安装VVI起搏器患者,随机分为右心室流出道间隔部起搏组和右心室心尖部起搏组,检测起搏器安置术前和术后12个月血N端脑钠肽前体(N-terminal pro-brain natriuretic peptide,NT-proBNP)水平。结果 两组起搏器安置术前、术后12个月血NT-proBNP水平,右心室流出道间隔部起搏组无明显变化(P>0.05),右心室心尖部起搏组显著升高(P<0.05)。两组术后12个月血NT-proBNP水平比较差异有统计学意义(P<0.05)。结论 右心室流出道间隔部起搏较右心室心尖部起搏对术后心脏收缩功能影响小,接近生理性起搏。

Observation of serum NT-proBNP level 12 months after operations of right ventricular outflow tract septum pacing and right ventricular apex pacing

Objective To compare the effect on cardiac systolic functions between the patients having accepted the operations of right ventricular outflow tract septum(RVOTS) pacing and right ventricular apex(RVA) pacing 12 months before. Methods One hundred patients with sick sinus syndrome who had implanted VVI pacemaker for the first time were observed and randomly divided into RVOTS-pacing group and RVA-pacing group. The levels of NT-proBNP were detected before and 12 months after the pacemaker implantation. Results In RVOTS-pacing group,there was no significant difference of serum NT-proBNP level before and 12 months after the operation(P>0. 05) while there was a significant increase in RVA-pacing group. The differences of serum NTproBNP levels between the two groups 12 months postoperatively also showed statistical significance(P<0. 05). Conclusion Compared with RVA pacing,RVOTS pacing had less influence on cardiac systolic function and more similar to physiological pacing.