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拉米夫定不良反应分析
引用本文:周璐,杨英,柯英.拉米夫定不良反应分析[J].中国药房,2006,17(8):612-613.
作者姓名:周璐  杨英  柯英
作者单位:四川绵阳四○四医院临床药学部,绵阳市,621000
摘    要:目的:探讨拉米夫定不良反应的一般规律和特点。方法:对1999年~2005年国内医药学术期刊报道的43例拉米夫定不良反应案例进行统计、分析。结果:拉米夫定不良反应多发生于8a~45a男性;发生时间无规律性;临床表现以神经系统反应和肝炎病情加重为主。结论:临床应重视拉米夫定的不良反应,以确保用药安全。

关 键 词:拉米夫定  不良反应  分析
文章编号:1001-0408(2006)08-0612-02
收稿时间:01 6 2006 12:00AM
修稿时间:02 15 2006 12:00AM

Literature Analysis on Lamivudine Adverse Reactions
ZHOU Lu,YANG Ying,KE Ying.Literature Analysis on Lamivudine Adverse Reactions[J].China Pharmacy,2006,17(8):612-613.
Authors:ZHOU Lu  YANG Ying  KE Ying
Institution:Dept.of Clinical Pharmacy, The 404th Hospital of Mianyang, Sichuan, Mianyang 621000, China
Abstract:OBJECTIVE:To discuss the general rules and characteristics of adverse drug reactions(ADRs)of lamivudine.METHODS:43national case reports of ADRs of lamivudine between1999and2005were classified and analyzed statistically.RESULTS:The affected patients ranged in age from8years to45years,with more males than females.There were no rules in the onset time of ADRs.The ADRS were mainly characterized by nervous system responses and aggravation of hepatitis in clinic.CONCLUSION:Great importance should be attached to ADRs of lamivudine to ensure the safety of drug use in clinic.
Keywords:Lamivudine  Adverse drug reaction  Analysis
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