肝硬化腹水并发自发性细菌性腹膜炎患者感染菌群分布及药敏分析

目的：探讨肝硬化腹水并发自发性细菌性腹膜炎（SBP）患者感染菌群分布及药敏情况。方法：回顾性分析78例临床诊断为肝硬化腹水并发SBP患者的临床资料、菌群分布及药敏结果。结果：78例患者中31例分离出病原菌,分离率39.74%,菌群分布以革兰阴性菌居多,占61.29%,分离率在前4位的病原菌依次是大肠埃希菌、金黄色葡萄球菌、克雷伯菌、凝固酶阴性葡萄球菌（CNS）。结论：肝硬化腹水患者易并发SBP,应根据药敏结果合理选择抗生素,并针对危险因素及高危人群采取有效的预防措施,从而降低SBP的发生率。

Pathogenic bacteria distribution of ascites and drug sensitivity analysis in liver cirrhosis with spontaneous bacterial peritonitis

Objective： To study the pathogenic bacteria distribution of ascites and drug sensitivity analysis in liver cirrhosis with spontaneous bacterial peritonitis. Methods： Retrospective analysis the clinical data of the 78 cases of liver cirrhosis patients with spontaneous bacterial peritonitis from June 2011 to June 2013,including gender,age, their corresponding bacterial distribution and drug sensitivity. Results： 31 pathogens were isolated from 78 cases and the isolation rate was 39. 74%. Ascites infection with G-bacterial distribution accounted for 61. 29%,isolation rate of the top five pathogens were Escherichiacoli, Staphylococcus Aureus, Klebsiella, Coagulase-negative staphylococcus. Conclusion： Liver cirrhosis patients are susceptible to spontaneous bacterial peritonitis, a reasonable choice of antibiotics should be based on the susceptibility,also effective preventive measures should be taken to reduce spontaneous bacterial peritonitis.