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Diurnal variation of serum calcium and phosphorus in postmenopausal women
Authors:Horace M. Perry III M.D.  Michael A. Province  Donna M. Droke  Ghi Su Kim  Sudah Shaheb  Louis V. Avioli
Affiliation:(1) Department of Medicine and Orthopedics, St. Louis University School of Medicine, 63104 St. Louis, Missouri;(2) Division of Biostatistics, Washington University School of Medicine, 63110 St. Louis, Missouri;(3) Division of Bone and Mineral Metabolism, Department of Medicine, Jewish Hospital of St. Louis and Washington University School of Medicine, 63110 St. Louis, Missouri;(4) Division of Endocrinology, St. Louis University Medical School, 1402 South Grand Boulevard, 63104 St. Louis, Missouri
Abstract:Summary Serum calcium, ionized calcium, and phosphorus have been obtained at hourly intervals in nine healthy postmenopausal women. The hourly means of ionized calcium and phosphorus demonstrate significant diurnal variation with a similar apogee, nadir, and periodicity (24 hours). These results are distinct from the diurnal variation of ionized calcium and phosphorus previously reported for young men and provide more evidence of an altered mineral hemostasis in postmenopausal women.
Keywords:Diurnal variation  Postmenopausal women  Young men  Ionized calcium and phosphate
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