Value of Evaluating Ovarian Response According to Basal FSH/LH Ratio

Controlled ovary hyperstimulation(COH) is an important stage in assistant reproduc- tion treatment. Due to patients’ individual differences, it can be great valuable in choosing property stimulation protocol, dose and predicting reproductive outcome to e…

Value of Evaluating Ovarian Response According to Basal FSH/LH Ratio

Objective To analyze the value of evaluating ovarian response to gonadotrophinstimulation according to patients basal FSH / LH ratio.Methods A total of 134 patients undergoing IVF-ET or ICSI were enrolled using short protocol. We studied their age, basal FSH, bFSH/LH ratio and some indexes which can represent ovarian response. Statistical evaluation was performed using logistic regression analysis and ROC curve to determine odds ratios(OR) and FSH/LH cutoffs.Results Among the patients whose bFSH were less than 8 IU/L, three odds ratios between the ovarian response index and their age, bFSH, bFSH/LH were no significant difference and bFSH/LH cutoff was 3.7. But among the patients those bFSH ≥ 8 IU/L,there were differences among the three OR and bFSH/LH cutoff was 3.3. The highest OR was between bFSH/LH ratio and ovarian response indexes, while the lowest was between bFSH and those indexes.Conclusions Among the patients who has lower ovary reserve (bFSH ≥ 8 IU/L), the ratio of bFSH/LH has superior value to age and basal FSH on evaluating ovarian response.