高血压及阿司匹林对鼻出血的影响分析

目的 探讨高血压及阿司匹林对于鼻出血发病及治疗的影响.方法 将267例鼻出血患者分为单纯鼻出血组62例,伴高血压的鼻出血组64例及鼻出血伴抗凝药应用组141例,比较单纯鼻出血、伴高血压的鼻出血及鼻出血伴抗凝药物应用患者鼻腔填塞治疗的有效率;比较填塞治疗有效者的复发率.结果 单纯鼻出血患者与伴高血压鼻出血患者有效率差异无统计学意义(96.7%比90.6%).鼻出血伴抗凝药物应用患者鼻腔填塞治愈率低于单纯鼻出血人群(84.4%比96.7%,P＜0.05);96.7%比90.6%,单纯鼻出血复发率与伴高血压的鼻出血组差异无统计学意义(6.5%比12.5%).结论 高血压不是鼻出血患者发病及填塞治疗效果的独立危险因子;抗凝药物的应用则可降低填塞效率并使鼻出血发病率增加,愈合时间延长.

Abstract：

Objective To report distinction of nasal packing with Vaseline gauze among patients with epistaxis, patients with epistaxis and hypertension, patients with epistaxis and anti-platelet drugs. Methods Two hundred and sixty-seven cases of epistaxis were divided into 62 cases of simple epistaxis group, 64 cases of epistaxis with hypertension and 141 cases of epistaxis with anticoagulant drug application group. We compared the efficiency of these groups with nasal packing therapy; as well as recurrence rate of the effective cases. Results Simple epistaxis patients and epistaxis patients with hypertension showed no significant difference regarding efficiency (96.7%vs 90.6%). Cure rate of nasal packing was lower in epistaxis patients with anticoagulant drug application than epistaxis cases (84.4% vs 96.7%, P ＜0.05); recurrence rate of simple epistaxis and epistaxis with hypertension had no significant difference (6.5% vs 12.5% ). Patients with epistaxis and antiplatelet drugs had a higher curative rate than those with epistaxis only. Conclusions Hypertension is not an independent risk factor for either therapy methods or packing time of patients with epistaxis. Meanwhile anti-platelet drugs play an important role in therapy methods and packing time of patients with epistaxis.

Analysis of hypertension and anti-platelet drugs' influence on epistaxis

Objective To report distinction of nasal packing with Vaseline gauze among patients with epistaxis, patients with epistaxis and hypertension, patients with epistaxis and anti-platelet drugs. Methods Two hundred and sixty-seven cases of epistaxis were divided into 62 cases of simple epistaxis group, 64 cases of epistaxis with hypertension and 141 cases of epistaxis with anticoagulant drug application group. We compared the efficiency of these groups with nasal packing therapy; as well as recurrence rate of the effective cases. Results Simple epistaxis patients and epistaxis patients with hypertension showed no significant difference regarding efficiency (96.7%vs 90.6%). Cure rate of nasal packing was lower in epistaxis patients with anticoagulant drug application than epistaxis cases (84.4% vs 96.7%, P ＜0.05); recurrence rate of simple epistaxis and epistaxis with hypertension had no significant difference (6.5% vs 12.5% ). Patients with epistaxis and antiplatelet drugs had a higher curative rate than those with epistaxis only. Conclusions Hypertension is not an independent risk factor for either therapy methods or packing time of patients with epistaxis. Meanwhile anti-platelet drugs play an important role in therapy methods and packing time of patients with epistaxis.