磁共振扩散张量成像对脊髓型颈椎病的初步研究

目的 探讨扩散张量成像对检出脊髓型颈椎病颈髓早期损伤的敏感性.方法 对13例健康志愿者和13例脊髓型颈椎病患者行常规MRI及扩散张量成像检查.测量C3～C7四组椎间盘层面的FA值、ADC值,并对所有受检者行颈髓纤维束重建.结果 病例组ADC值大于对照组(t =8.495,P ＜0.001);病例组FA值小于对照组(t =-14.328,P ＜0.001),两者皆有统计学意义.病例组中约92.3 %(12/13)患者脊髓受压部位伪彩图信号改变;约30.8% (4/13)患者T2WI脊髓内可见高信号,扩散张量成像比常规MRI对脊髓损伤更加敏感(P =0.002).结论 扩散张量成像可以提供脊髓的病

Preliminary study of diffusion tensor imaging in cervical spondylotic myelopathy

Objective:To explore the sensibility of diffusion tensor imaging(DTI) in early detecting spinal cord injury in cervical spondylotic myelopathy.Materials and Methods:Cervical routine MRI and DTI were performed in 13 healthy volunteers and 13 patients with cervical spondylotic myelopathy.The radiological findings were analyzed,and the apparent diffusion coefficient(ADC) values and the fractional anisotropy(FA) values were calculated,and spinal cord fiber bundle was reconstructed.Results:Compared with control group,the mean ADC and FA values were higher(t=8.495,P<0.001) and the mean FA was lower(t=﹣14.328,P<0.001).The DTI color maps found abnormal signal at the compressed spinal cord.T2WI showed high signal at the compressed spinal cord in 4/13(30.8%) patients.Fisher statistics proved that DTI was more sensitive than routine MRI(P=0.002).Conclusion:DTI can provide information about the pathology.It is more sensitive in early detecting spinal cord injury in cervical spondylotic myelopathy than routine MRI.