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神经精神疾病的功能磁共振成像研究进展
引用本文:王秀丽,黄晓琦,龚启勇. 神经精神疾病的功能磁共振成像研究进展[J]. 磁共振成像, 2012, 3(1): 61-68
作者姓名:王秀丽  黄晓琦  龚启勇
作者单位:四川大学华西医院心理卫生中心;四川大学华西医院放射科
基金项目:国家自然科学基金项目(编号:81171488)资助
摘    要:脑功能磁共振成像(fMRI)能在活体人脑定位各功能脑区,研究脑的功能连接.本文基于任务态和静息态的应用模式,自局部脑区功能活动、脑区间功能连接及脑功能网络层面,综述了脑功能磁共振成像在神经精神疾病发病机制、诊断、治疗及预后等方面的临床研究现状.今后需进行多学科、多方法 相结合的纵向研究,探索神经精神疾病特异的功能影像学...

关 键 词:神经精神疾病  磁共振成像  功能性  任务态  静息态

Functional MRI in neuropsychiatric disorders
WANG Xiu-li,HUANG Xiao-qi,GONG Qi-yong. Functional MRI in neuropsychiatric disorders[J]. Chinese Journal of Magnetic Resonance Imaging, 2012, 3(1): 61-68
Authors:WANG Xiu-li  HUANG Xiao-qi  GONG Qi-yong
Affiliation:1Mental health center,West China Hospital,Sichuan University,Chengdu 6l0041,China 2Department of Radiology,West China Hospital,Sichuan University,Chengdu 6l0041,China
Abstract:Brain functional magnetic resonance imaging(fMRI) can help locate the functional areas in human brain,and study the functional connectivity between the brain regions.Based on the modes of the task state and resting state,present review summarized clinical advances of fMRI in the pathogenesis,diagnosis,treatment and prognosis of neuropsychiatric disorders from the local brain function to the functional connectivity beween brain regions to the brain functional network.Future researches need to combine multi-methods and to cooperate with multi-disciplines to explore specific neuroimaging markers in those disorders.Thus imaging technique may eventually be used to help with early detection,early intervention and prognosis judgement.
Keywords:Neuropsychiatric disorders  Magnetic resonance imaging,functional  Task state  Resting state
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