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Depressive symptoms in relation to physical functioning in pulmonary hypertension
Authors:Karl J. Looper  Andrena Pierre  John J. Sigal
Affiliation:a Department of Psychiatry, Sir Mortimer B. Davis - Jewish General Hospital, 3755 Cote Ste-Catherine Road, Montreal, Quebec, Canada H3T 1E2
b Institute of Community and Family Psychiatry, Sir Mortimer B. Davis - Jewish General Hospital, 4333 Cote Ste-Catherine Road, Montreal, Quebec, Canada H3T 1E4
c Center for Pulmonary Vascular Disease, Sir Mortimer B. Davis - Jewish General Hospital, 3755 Cote Ste-Catherine Road, Montreal, Quebec, Canada H3T 1E2
Abstract:

Objective

To investigate the association between depressive symptoms and physical functioning in pulmonary hypertension (PH) patients.

Methods

Fifty-two patients diagnosed with precapillary or postcapillary PH completed self-report questionnaires of depressive symptoms and physical functioning. Cardiac catheterization reports of patients were reviewed for hemodynamic variables.

Results

Physical functioning was significantly associated with depressive symptoms on bivariate analysis. On multivariate analysis, after controlling for demographic and hemodynamic variables, depressive symptoms accounted for 9% of variance in physical functioning.

Conclusion

The association of depressive symptoms with decreased physical functioning in PH patients indicates the need for longitudinal research regarding the possible effect of depression on disease outcomes in this population.
Keywords:Cardiac catheterization   Depression   Emotional state   Hemodynamic   Physical functioning   Pulmonary hypertension
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