| Abstract: | The pathogenesis of trachoma is discussed
including the conjunctival cytology, follicular
pathology and chlamydial toxin pathogenic ac-
tion on human eyes. It is believed that the toxin
is the main factor in producing the acute symp-
toms. Proliferative inflammation runs a chronic
course and repeated infections induce delayed
hypersensitivity. The severity of the morbid
condition is related closely to host immunolo-
gic status against Chlamydia. Severe trachoma
represents immunopathologic changes aft.er re-
peated infections. The key to prevention and
treatment of trachoma lies in energetic treat-
ment of acute cases and exacerbated cases and
control of transmission. In treating severe tra-
choma cases with active pannus, corticosteroids
should be added to the antichlamydia drugs. |
