| Abstract: | Serum enzyme aralysis has been used in the
diagnosis of hepatobiliary diseases for many
years. In order to enhance the diagnostic value
of enzymology, attention has been directed to
the different molecular forms (isozymes) of a
given enzyme. Since 1977, we have studied the
clinical application of isozymes of lactate dehy-
drogenase (LDH), glutamate-oxalacetate transa-
minase (GOT), r-glutamyl transpeptidase
(GGT), alkaline phosphatase and adenosine dia-
minase. The results of our study of LDH is-
ozyme and GOT isozyme are reported in this
paper. All cases were hospitalized and evaluated
carefully. The diagnosis was made according to
the widely accepted clinical criteria and in about
half of the cases the diagnoses were proven by
pathological examination through_biopsy and/or
operation. Normal sera were obtained from
blood bank donors in our hospital. |
