Ribosomal RNA synthesis after infection with adenovirus type 2

The synthesis of mature cytoplasmic ribosomal RNA was preferentially inhibited in comparison to 4S RNA in T6a (hamster) cells infected with adenovirus type 2, but not in uninfected controls. No effect was observed in 3T3–4E (mouse) cells infected with adenovirus type 2. When T6a-3T3-4E hybrids were infected with this virus, no significant change in the proportion of hamster and mouse cytoplasmic ribosomal RNA synthesized was detected, in comparison to uninfected hybrid cells.