Nephron-sparing surgery in children with primary renal tumor: indications and results |
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Authors: | Cozzi Denis Andrew Zani Augusto |
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Affiliation: | Pediatric Surgery Unit, Policlinico Umberto I, University of Rome "La Sapienza", Rome, Italy. da.cozzi@uniromal.it |
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Abstract: | Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with "low-risk" or stage I "intermediate-risk" WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy. |
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