贵阳地区孕期夫妇地中海贫血血液学筛查的研究

目的：对贵阳地区孕期夫妇进行地中海贫血（以下简称地贫）血液学筛查，预防和控制地贫重症患儿的出生。方法：采用一管定量筛查法及ＨｂＡ、ＨｂＦ定量法。结果：在贵阳医学院附院产科围产期检查的３２４例孕妇及其配偶进行血液学筛查，检出地贫阳性病例１４例，其中二对孕期夫妇双方均为阳性，患病率为４．３２％。结论：这是首次在贵阳地区进行的筛查研究工作。为产前基因诊断奠定了基础。

Antenatal Screening of Thalassemia in Guiyang Area

Objective. To screen pregnant women and their hus-bands to investigate the carrier rate of thalassemia in general popula-tion. Methods. HbA2 and HbF quantitative analysis and screening ofone tube quantity. Results. Of all 324 individuals screening for thalas-semia 14. cases were found. the two couples of them were positivethalassemia. The incidence of this disease was 4. 32%. Conclusion.This work build the foundation for prenatal diagnosis of the thalasse-mia.