首页 | 本学科首页   官方微博 | 高级检索  
检索        


TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis
Authors:Sara Van Mossevelde  Federica Perrone  Lubina Dillen  Bavo Heeman  Veerle Bäumer  Sebastiaan Engelborghs  Jan De Bleecker  Jonathan Baets  Ellen Gelpi  Ricardo Rojas‐García  Jordi Clarimón  Alberto Lleó  Janine Diehl‐Schmid  Panagiotis Alexopoulos  Robert Perneczky  Matthis Synofzik  Jennifer Just  Ludger Schöls  Caroline Graff  Håkan Thonberg  Barbara Borroni  Alessandro Padovani  Albena Jordanova  Stayko Sarafov  Ivailo Tournev  Alexandre de Mendonça  Gabriel Miltenberger‐Miltényi  Frederico Simões do Couto  Alfredo Ramirez  Frank Jessen  Michael T Heneka  Estrella Gómez‐Tortosa  Adrian Danek  Patrick Cras  Rik Vandenberghe  Peter De Jonghe  Peter P De Deyn  Kristel Sleegers  Marc Cruts  Christine Van Broeckhoven  Silvia Testi
Institution:1. Center for Molecular Neurology, VIB, Antwerp, Belgium;2. Institute Born‐Bunge, University of Antwerp, Antwerp, Belgium;3. Department of Neurology, Antwerp University Hospital, Edegem, Belgium;4. Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium;5. Department of Neurology, University Hospital Ghent and University of Ghent, Ghent, Belgium;6. Neurological Tissue Bank of the Biobanc ‐ Hospital Clinic‐Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain;7. Department of Neurology, IIB Sant Pau, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain;8. Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain;9. Department of Psychiatry and Psychotherapy, Technische Universit?t München, München, Germany;10. Neuroepidemiology and Ageing Research Unit, School of Public Health, The Imperial College of Science, Technology and Medicine, London, UK;11. West London Cognitive Disorders Treatment and Research Unit, West London Mental Health Trust, London, UK;12. Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and Centre of Neurology, Tübingen, Germany;13. German Research Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany;14. Department of Neurobiology, Care Sciences and Society (NVS), KI‐Alzheimer Disease Research Center, Karolinska Institutet, Stockholm, Sweden;15. Department of Geriatric Medicine, Genetics unit, Karolinska University Hospital, Stockholm, Sweden;16. Neurology Unit, University of Brescia, Brescia, Italy;17. Department of Biochemistry, Molecular Medicine Center, Medical University‐Sofia, Sofia, Bulgaria;18. Department of Neurology, Medical University‐Sofia, Sofia, Bulgaria;19. Department of Cognitive Science and Psychology, New Bulgarian University, Sofia, Bulgaria;20. Hospital Santa Maria, Lisbon, Portugal;21. Faculty of Medicine and Institute of Molecular Medicine, University of Lisbon, Lisbon, Portugal;22. Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany;23. Institute of Human Genetics, University of Bonn, Bonn, Germany;24. Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany;25. German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany;26. Clinical Neuroscience Unit, Department of Neurology, University of Bonn, Bonn, Germany;27. Department of Neurology, Fundación Jiménez Díaz, Madrid, Spain;28. Department of Neurology, Ludwig‐Maximilians‐Universit?t München, Munich, Germany;29. German Center for Neurodegenerative Diseases (DZNE), Munich, Germany;30. Department of Neurosciences, Faculty of Medicine, KU Leuven, Leuven, Belgium;31. Department of Neurology, University Hospitals Leuven, Leuven, Belgium
Abstract:
Keywords:TANK‐Binding Kinase 1  TBK1  frontotemporal dementia  FTD  amyotrophic lateral sclerosis  ALS  mutations  NFκ  B luciferase reporter assay
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号