Synthesis and antiinflammatory activity of N-[1-(5-R-Oxy-2-methylbenzofuran-3-yl)ethyl]-N-hydroxyureas |
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| Authors: | S. A. Zaitsev O. A. Onuchina L. M. Alekseeva A. P. Arzamastsev M. A. Kalinkina V. G. Granik |
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| Affiliation: | (1) State Scientific Center for Antibiotics, Moscow, Russia;(2) Sechenov Moscow Medical Academy, Moscow, Russia |
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| Abstract: | Two benzofuran derivatives — analogs of 5-lipoxygenase antagonist zileuton — have been synthesized and tested. It is established that both compounds possess antiinflammatory activity. __________ Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39, No. 12, pp. 17–20, December, 2005. |
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