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Completely converting a blood service region to the use of safer plasma
Authors:McCarthy L J  Danielson C F  Rothenberger S S  Parker C  Weidner J  Miraglia C  Matus D  Waxman D
Institution:Department of Pathology and Laboratory Medicine, Indiana University. Indianapolis 46202-5283, USA.
Abstract:BACKGROUND: Three types of plasma are widely available for transfusion. Two plasma components, FFP donor retested (FFP-DR), and solvent/detergent-treated plasma (SDP), are now considered to be safer from infectious complications than FFP. STUDY DESIGN AND METHODS: A large regional blood center attempted to provide FFP-DR exclusively to all its 42 hospitals. Significant planning, increases in computer capabilities, and expansion of component storage areas were completed before initiation of this program. RESULTS: During the first 6 months of the FFP-DR program, the blood center was not able to supply the entire region exclusively with FFP-DR. Consequently, SDP was utilized to supplement the program and to successfully and completely convert the region's 42 hospitals to the use of safer plasma. CONCLUSION: Two new plasma components were utilized to completely convert a blood service region to the use of safer plasma.
Keywords:CIRBC = Central Indiana Regional Blood Center  CPP = cryopoor FFP  DR = donor retested  MAC = Medical Advisory Committee  S/D = solvent/detergent  SDP = solvent/detergent-treated plasma  TAC = Technical Advisory Committee  TNBP = tri(N-butyl)phosphate
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