On the prevalence of bipolar disorder in epilepsy |
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| Authors: | Mula Marco Schmitz Bettina Jauch Regina Cavanna Andrea Cantello Roberto Monaco Francesco Trimble Michael R |
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| Institution: | aThe Neuropsychiatry Research Group, Department of Neurology, Amedeo Avogadro University, C.so Mazzini, 18-28100 Novara, Italy;bThe Epilepsy Center, Department of Neurology, Amedeo Avogadro University, C.so Mazzini, 18-28100 Novara, Italy;cUniversitätsmedizin-Charité, Department of Neurology, Campus Virchow-Klinikum, Seizure Clinic, Berlin, Germany;dInstitute of Neurology, University College, London, UK |
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| Abstract: | Although mood disorders represent a frequent psychiatric comorbidity in epilepsy, data on bipolar disorder (BD) are still limited, and the role of possible specific confounding variables (seizures and antiepileptic drug therapy) has never been considered. Data for 143 adult outpatients with epilepsy assessed with the Mini International Neuropsychiatric Interview Plus Version 5.0.0 using the Epilepsy Addendum for Psychiatric Assessment, the Mood Disorder Questionnaire, and the Interictal Dysphoric Disorder Inventory revealed that 11.8% had the Diagnostic and Statistical Manual of Mental Disorders-based diagnosis of BD, only 1.4% of whom could be considered as having “pure” BD, because in all other cases BD symptoms were related to phenotype copies of BD such as interictal dysphoric disorder of epilepsy, postictal manic or hypomanic states, and preictal dysphoria. |
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| Keywords: | Epilepsy Bipolar disorder Interictal dysphoric disorder Depression |
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