Aptamer-conjugated nanomaterials and their applications |
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| Authors: | Yang Liu Zhang Xiaobing Ye Mao Jiang Jianhui Yang Ronghua Fu Ting Chen Yan Wang Kemin Liu Chen Tan Weihong |
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| Affiliation: | State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha, PR China. |
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| Abstract: | The combination of aptamers with novel nanomaterials, including nanomaterial-based aptamer bioconjugates has attracted considerable interest and has led to a wide variety of applications. In this review, we discuss how a variety of nanomaterials, including gold, silica and magnetic nanoparticles, as well as carbon nanotubes, hydrogels, liposomes and micelles, have been used to functionalize aptamers for a variety of applications. These aptamer functionalized materials have led to advances in amplified biosensing, cancer cell-specific recognition, high-efficiency separation, and targeted drug delivery. |
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