儿童脑脓肿37例临床特征和治疗随访

目的 阐明儿童脑脓肿临床特征，探讨脑脓肿的治疗方法。方法 对３７例经ＣＴ和ＭＲＩ确诊为脑逐月中的患儿临床特征进行分析，对疗效进行观察，对其中２３例进行病后３个月～５年的随访。结果 ３７例患儿中未查到原发感染灶的２９例（７８％），以癫痫为首发症状者２０例（５４％），头痛者１８例（４９％），发热者１３例（３５％），３０例经保守治疗１１例治愈，１２例好转，总有效率７７％；７例采取外科治疗，１例治愈，３例

Clinical characteristics and follow up of treatment in 37 cases of brain abscess in children

Objective To clarify the clinical characteristics and discuss the treatments of brain abscess in children Method The clinical characteristics were analyzed in 37 patients with brain abscess diagnosed by CT or MRI,and 23 of them were followed up for a period of 3 months to 5 years Results The primary infection focus could not be found in 29 patients (78%) The seisure as the first symptom was present in 20 patients (54%); 13 patients (35%) had fever and 18 (49%) had headache Thirty patients were treated with antibiotics through intravenous injection for 3 to 6 weeks, 11 of them recovered completely, 12 had improvement, the treatment was effective in 77% of the patients; of the 7 patients who received surgery,1 recovered, 3 got improved Eight recovered patients were followed up, in 5 of them there were no abnormal findings on CT and MRI, 3 patients without CT or MRI examination were symptoms free. Six of 13 improved patients recovered completly, 1 patient relapsed, 1 had hemiplegia of the right side, 5 patients without CT or MRI examination had no symptoms. Conclusions The causes of brain abscess in 78% of patients were obscure, so most of clinical symptoms of brain abscess in children may not be representative The conservative treatment is the main therapy Follow up is an important method for evaluating long term effects of brain abscess treatment.