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抗生素对小儿呼气氢试验的影响
引用本文:叶彩霞,王茂贵,王宝西.抗生素对小儿呼气氢试验的影响[J].中华儿科杂志,1999,37(7):415-417.
作者姓名:叶彩霞  王茂贵  王宝西
作者单位:YE Caixia,WANG Maogui,WANG Baoxi,et al Department of Pediatrics,Tangdu Hospital,Fourth Military Medical University,Xian 710038
摘    要:目的探讨抗生素对呼气氢试验(BHT)的影响。方法应用HD1型呼气氢测定仪,检测抗生素应用前后75例住院患儿空腹呼气氢(FBH)值和其中23例患儿乳果糖氢呼吸试验(LHBT)的结果,并与231例健康儿FBH比较。结果抗生素应用后FBH[(1950±124)×百万分浓度(10-6)]较应用前(3594±298)×10-6明显降低(t=495,P<0001);住院患儿抗生素应用前FBH(3594±298)×10-6与健康儿(1452±010)×10-6比较,(u=483,P<001);应用抗生素患儿口服乳果糖后呼气氢值无明显变化。结论住院患儿抗生素应用前,FBH较健康患儿明显升高;抗生素应用后FBH较应用前明显降低,LHBT呈假阴性结果。提示肠道氢产生受抑制。

关 键 词:抗生素类  呼吸试验  儿童  

Effect of antibiotics on breath hydrogen test in children
YE Caixia,WANG Maogui,WANG Baoxi,et al.Effect of antibiotics on breath hydrogen test in children[J].Chinese Journal of Pediatrics,1999,37(7):415-417.
Authors:YE Caixia  WANG Maogui  WANG Baoxi  
Institution:YE Caixia,WANG Maogui,WANG Baoxi,et al Department of Pediatrics,Tangdu Hospital,Fourth Military Medical University,Xian 710038
Abstract:Objective To evaluate influences of antibiotics on breath hydrogen test in children Methods Fasting breath hydrogen (FBH) test and lactulose hydrogen breath test (LHBT) were respectively performed by using HD1 breath hydrogen detector for 75 and 23 inpatients before and after receiving antibiotics FBH of 231 healthy controls was determined Results After antibiotics were given, FBH was (195124)10-6, being lower than that before antibiotics use The FBH value obtained before antibiotics use was significantly higher in 75 inpatients compared with 231 healthy controls After antibiotics were given, LHBT did not significantly change Conclusion The hydrogen production was markedly depressed after antibiotic therapy FBH values were significantly higher in inpatients with infectious diseases compared with healthy controls
Keywords:AntibioticsBreath testsChildHydrogen  
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