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肾移植对尿毒症患者生精功能的影响
引用本文:俞建军,徐月敏,张华.肾移植对尿毒症患者生精功能的影响[J].中华男科学杂志,2005,11(11):822-824.
作者姓名:俞建军  徐月敏  张华
作者单位:1. 上海交通大学附属第六人民医院泌尿外科,上海,200233
2. 浙江大学医学院附属第一医院男性学实验室,浙江,杭州,310003
摘    要:目的:探讨尿毒症患者肾移植后睾丸生精功能的改变。方法:比较30例男性尿毒症患者,肾移植前后精液参数变化及精子超微结构改变。结果:肾移植术后3个月精子活力与移植前比较显著升高(70.08±2.86)%vs(36.04±8.01)%,P<0.01],活率显著增加(76.15±3.75)%vs(39.27±4.14)%,P<0.01],运动速度显著加快(16.80±1.11)μm/svs(8.43±2.01)μm/s,P<0.01]。精子超微结构发现,肾移植后支持细胞、顶体及线粒体的结构趋向正常。结论:肾移植可显著改善尿毒症患者的生精功能。

关 键 词:尿毒症  肾移植  生精功能
文章编号:1009-3591(2005)11-0822-03
收稿时间:2004-11-26
修稿时间:2005-02-24

Kidney Transplantation Improves Spermatogenic Function in Patients with Uremia
YU Jian-jun,XU Yue-min,ZHANG Hua.Kidney Transplantation Improves Spermatogenic Function in Patients with Uremia[J].National Journal of Andrology,2005,11(11):822-824.
Authors:YU Jian-jun  XU Yue-min  ZHANG Hua
Institution:Department of Urology, Sixth Peoples Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China. yujj917@163.com
Abstract:OBJECTIVE: To study the changes of testicular spermatogenic function after kidney transplantation. METHODS: Thirty male patients with uremia underwent kidney transplantation. Semen analyses were made and sperm ultrastructural changes were studied before and after the operation. RESULTS: Sperm viability, motility and movement velocity were significantly higher in the postoperative group than in the preoperative group (70.08 +/- 2.86 vs (36.04 +/- 8.01)], (76.15 +/- 3.75)% vs (39.27 +/- 4.14)%], (16.80 +/- 1.11) microm/s vs (8.43 +/- 2.01)] micro/s, respectively (P < 0.01). Sertoli cell, acrosome and mitochondria structures inclined to normal after kidney transplantation. CONCLUSION: Kidney transplantation can significantly improve spermatogenic function in patients with uremia.
Keywords:uremia  kidney transplantation  spermatogenic function
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