| 牛磺酸对大鼠心肌梗塞及血管活性物质的影响 |
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| 引用本文： | 赵云涛 宫长宁. 牛磺酸对大鼠心肌梗塞及血管活性物质的影响[J]. 标记免疫分析与临床, 1995, 2(1): 22-24,14 |
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| 作者姓名： | 赵云涛 宫长宁 |
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| 作者单位： | [1]中国人民解放军海军总医院 [2]北京医科大学 |
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| 摘 要： | 本实验结扎在鼠左冠状动脉前降支建立心肌梗塞模型，观察牛磺酸对心肌梗塞的治疗作用及对血和活性物质的影响。结果显示外源性注射牛磺酸可减少大鼠心肌梗塞坏死面积和缩小梗塞范围：血清ＣＰＫ、ＣＫ ＭＢ活性下降，ＭＤＡ含量降低；牛磺酸还可使血浆内皮素、甘丙素、Ｐ物质、ｃＡＭＰ和ｃＧＭＰ水下下降，提示牛磺酸对急性心肌缺血坯死有明显的保护作用。
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| 关 键 词： | 牛磺酸 心肌梗塞 血管活性物质 大鼠 |
Effects of Taurine on Myocardial Infarcts and Vasoactive Substances in Rats |
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| Zhao Yuntao,Shi Xiangyun,Li Zhongan,et al.. Effects of Taurine on Myocardial Infarcts and Vasoactive Substances in Rats[J]. Labeled Immunoassays and Clinical Medicine, 1995, 2(1): 22-24,14 |
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| Authors: | Zhao Yuntao Shi Xiangyun Li Zhongan et al. |
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| Abstract: | Myocardial infarction of rats was produced by ligation of left anterior descending coronary artery to study the therapeutic effects of taurine on infarcts as well as vasoactive substances. Taurine reduced the size of infarcts,inhibited plasma activities of CPK and CK-MB,lowered plasma content of MDA. Taurine also decreased plasma levels of ET,GAL,SP,cAMP and cGMP. The results suggest that taurine has beneficial effects on acute myocardial infarction. |
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| Keywords: | Taurine Myocardial infarction Galanin Endothelin Nucleotides.cyclic |
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