| 瘦素及其受体在家兔下颌下腺和胃的表达与分布 |
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| 引用本文： | 彭彦霄,杨春暖,王倩,吴学平,李玉磊.瘦素及其受体在家兔下颌下腺和胃的表达与分布[J].皖南医学院学报,2007,26(4):245-246,F0003. |
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| 作者姓名： | 彭彦霄 杨春暖 王倩 吴学平 李玉磊 |
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| 作者单位： | 1. 皖南医学院,组织胚胎学教研室,安徽,芜湖,241002
2. 菱花集团有限公司,山东,济宁,272000 |
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| 基金项目： | 安徽省高校青年教师科研资助计划基金 |
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| 摘 要： | 目的:探讨瘦素及其受体在家兔下颌下腺和胃的分布和意义。方法:免疫组织化学SABC法。结果:兔下颌下腺的纹状管和小叶间导管上皮细胞呈瘦素及其受体免疫反应阳性,阳性物质分布在胞质,细胞核为阴性反应。胃底腺壁细胞亦呈瘦素及其受体免疫反应阳性,细胞核为阴性反应。结论:家兔下颌下腺和胃底腺壁细胞中有瘦素及其受体的表达,提示瘦素可能参与下颌下腺和胃分泌活动的调节。
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| 关 键 词： | 瘦素 瘦素受体 免疫组织化学 下颌下腺 胃 兔 |
| 文章编号： | 1002-0217（2007）04-0245-03 |
| 修稿时间： | 2007-03-08 |
Expression and distribution of leptin and leptin receptor in submandibular gland and stomach of rabbits |
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| PENG Yan-xiao,YANG Chun-nuan,WANG Qian,WU Xue-ping,LI Yu-lei.Expression and distribution of leptin and leptin receptor in submandibular gland and stomach of rabbits[J].Acta Academiae Medicinae Wannan,2007,26(4):245-246,F0003. |
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| Authors: | PENG Yan-xiao YANG Chun-nuan WANG Qian WU Xue-ping LI Yu-lei |
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| Institution: | Department of Histology and Embryology, Wannan Medical University,Wuhu 241002, China |
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| Abstract: | Objective:To study the location and distribution of leptin and leptin receptor in submandibular gland and stomach of rabbit.Methods: Submandibular gland and stomach from rabbits were observed by immunohistochemical SABC staining.Results: The striated duct and interlobular duct demonstrated evidently positive,but the acini were negative.The positive substance was distributed in the cytoplasm with negative nuclei.The parietal cells of gastric gland presented with leptin and leptin receptor positive immunoreactivity.Conclusion:Leptin and leptin receptor were widely expressed in submandibular gland and stomach of rabbit,which suggests that submandibular gland and gastric gland might be regulated by follicle stimulating leptin through leptin receptor. |
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| Keywords: | leptin leptin-receptor immunohistochemistry submandibular gland stomach rabbit |
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