| 覆盆子药材质量标准研究 |
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| 引用本文： | 郭卿,;付辉政,;周国平,;杨毅生,;钟瑞建. 覆盆子药材质量标准研究[J]. 江西中医学院学报, 2014, 0(3): 51-54 |
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| 作者姓名： | 郭卿, 付辉政, 周国平, 杨毅生, 钟瑞建 |
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| 作者单位： | [1]江西省食品药品检验所,江西省药品与医疗器械质量工程技术研究中心,江西南昌330029; [2]江西中医药大学,江西南昌330004 |
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| 基金项目： | 江西省科技计划项目（20132BBG70039）; 国家药典委员会资助项目 |
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| 摘 要： | 目的：建立覆盆子药材的质量标准,为该药材植物资源的开发利用提供科学依据。方法：采用薄层色谱法,水分测定法,灰分测定法,浸出物测定法及高效液相色谱（HPLC）法。结果：10批覆盆子药材水分含量为9.56%~10.60%,总灰分含量为4.25%~7.59%,酸不溶性灰分含量为0.46%~0.89%,水溶性浸出物含量为10.45%~14.19%;山柰酚-3-O-芸香糖苷在0.0789~1.1835μg之间呈良好的线性,平均回收率为101.9%,RSD=0.7%（n=6）;TLC鉴别结果满意。结论：通过研究建立了覆盆子的质量标准。
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| 关 键 词： | 覆盆子 山柰酚-3-O-芸香糖苷 高效液相色谱法 质量控制 |
Investigation on Quality Standard of Rubus Chingii |
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| Affiliation: | GUO Qing, FU Hui- zheng, ZHOU Guo-ping, YANG Yi- sheng, ZHONG Rui-jian( 1. Jiangxi Provicial Institute for Drug and Food Control, Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality, Nanchang 330029, China; 2. Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.) |
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| Abstract: | Objective：To provide scientific basis for the utilization and development of Rubus chingii by setting up the quality control specification of Rubus chingii.Method：Moisture,ash and extractum were determined by aquametry,method of ash determination and extract measurement,respectively.And the bioactive constituents were analyzed by HPLC and TLC.Result：The 10 batch of Rubus chingii moisture content was 9.56% ~ 10.60%,the total ash contents was 4.25% ~ 7.59%,the acid insoluble ash content was 0.46%~ 0.89%,the water extract content was 10.45% ~ 14.19%;For the HPLC quantitation method,the calibration curves were linear between 0.0789 ~ 1.1835μg.The average recovery rate was 101.9%,and RSD was 0.7%（n = 6）;The TLC identification results were satisfactory.Conclusion：The established method can be used for the quality control of Rubus chingii. |
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| Keywords: | Rubus chingii Kaempferol-3-O-rutinoside HPLC Quality control |
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