| 分光光度法测定安痛定注射液中氨基比林含量 |
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| 引用本文： | 卢庆祥,张培字,于莉. 分光光度法测定安痛定注射液中氨基比林含量[J]. 中国药业, 2009, 18(5): 26-27 |
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| 作者姓名： | 卢庆祥 张培字 于莉 |
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| 作者单位： | 枣庄科技职业学院医学系,山东,滕州,277500 |
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| 摘 要： | 目的 采用分光光度法测定药物的氨基比林含量。方法在吐温-80存在的情况下，采用Fe^3＋、邻菲罗啉-硫氰化铵分光光度法测定药物的氨基比林含量，测定波长525nm。结果氨基比林的质量浓度在0～1．0×10^-2g／L范围内符合比尔定律，回归方程A=0．03804＋0．9009C（r=0．9928），回收率范围为98．6％～102．3％。结论分光光度法简便、快速、灵敏，可用于测定安痛定中的氨基比林含量。
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| 关 键 词： | 氨基比林 Fe^2＋-邻菲罗啉配合物 分光光度法 含量 |
Dtermination of Amidopyrine in Amidopyrine Injection by Spectrophotometric Method |
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| Lu Qingxiang,Zhang Peiyu,Yu Li. Dtermination of Amidopyrine in Amidopyrine Injection by Spectrophotometric Method[J]. China Pharmaceuticals, 2009, 18(5): 26-27 |
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| Authors: | Lu Qingxiang Zhang Peiyu Yu Li |
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| Affiliation: | (Department of Medicine, Zaozhuang Vocational College of Science and Technology, Tengzhou, Shandong, China 277500) |
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| Abstract: | Objective To determine amidopyrine in Amidopyrine Injection by spectrophotometry. Methods Amidopyrine was determined by spectrophotometry with Fe（ Ⅲ ）, phenanthrotine and NH4SCN in the presence of Tween-80 at the detection wavelength of 525 nm. Results Beer s law was obeyed in the range of 0 - 1.0 × 10^-2 g/L for amidopyrine. The regression equation： A = 0. 038 04 ＋ 0. 900 9 C（ r = 0. 992 8）. The recovery rate was 98.6% -102. 3%. Conclusion The method is simple, rapid and reproducible. It can be applied to the determination of amidopyrine in Amidopyrine Injection. |
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| Keywords: | amidopyrine Fe^2＋ - phenanthroline spectrophotometry content |
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