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Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagement
Authors:Gambhir Vandana  Kim Julia  Siddiqui Sarah  Taylor Michelle  Byford Valarie  Petrof Elaine O  Jones Glenville  Basta Sameh
Affiliation:a Department of Microbiology and Immunology, Queen's University, Kingston, Ontario, Canada
b Department of Gastrointestinal Diseases Research Unit, Queen's University, Kingston, Ontario, Canada
c Department of Biochemistry, Queen's University, Kingston, Ontario, Canada
Abstract:
Keywords:TLR, toll-like receptor   TLR-L, TLR ligand   pAPC, professional antigen presenting cells   DC, dendritic cell    , macrophage   FCM, flow cytometry   NO, nitric oxide   LPS, lipopolysaccharide   CYP24A1, 24-hydroxylase gene   CYP24A1, 24-hydroxylase enzyme   VDR, vitamin D receptor   HPLC, high performance liquid chromatography   BMDC, bone marrow-derived dendritic cell
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