| 离体大鼠海马神经元自发放电活动一般特征的研究 |
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| 引用本文： | 杨润生,潘盛武,方颖,杨盛昌. 离体大鼠海马神经元自发放电活动一般特征的研究[J]. 生物医学工程研究, 2009, 28(1) |
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| 作者姓名： | 杨润生 潘盛武 方颖 杨盛昌 |
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| 作者单位： | 1. 解放军第181医院烧伤整形中心,动物实验室,桂林,541002
2. 广西师范大学生命科学学院,解剖生理学教研室,桂林,541002 |
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| 摘 要： | 观察离体大鼠海马锥体细胞的生理电发放模式.在脑脊液孵育下,将玻璃微电极插入到离体大鼠海马脑片锥体细胞附近,进行胞外电脉冲记录,微机记录并保存电信号.共观察到海马部神经元自发放电主要呈5种特征,分别为不规则发放、单波规则发放、紧张发放、阵发排放及周期排放型等形式.说明神经元的生理电发放模式可能与细胞的排列次序、生理应答呈一定的相关性.
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| 关 键 词： | 大鼠海马 微电极 脑片 自发放电 |
The General Electric Activity Characters of the Rat Hippocampus Ex-vivo Pyramidal Cells |
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| YANG Runsheng,PAN Shengwu,FANG Ying,YANG Shengchang. The General Electric Activity Characters of the Rat Hippocampus Ex-vivo Pyramidal Cells[J]. Journal Of Blomedical Englneerlng Research, 2009, 28(1) |
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| Authors: | YANG Runsheng PAN Shengwu FANG Ying YANG Shengchang |
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| Affiliation: | 1.Animal Experiment Lab;Burn Plastic Center;No.181 Hospital of PLA;Guilin 541002;China;2.Science Life College;Guangxi Normal University;Guilin 541002 |
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| Abstract: | To study the general characters of the rat hippocampus of the spontaneous electric activity of the ex-vivo pyramidal cells.We recorded the electrophysiology near the hippocampal pyramidal cells of the rat limbic system by capillary glass microelectrode with continous perfusion of the artificial cerebrospinal fluid(ACSF).Results showed that five characters of spontaneous were recorded by the rat hippocampal cells,they were un-regulation release,single wave regular release,intension release,paroxysm release a... |
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| Keywords: | Rat hippocampus Microelectrode Brain slice Spontaneous discharge |
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