| 反相高效液相色谱法测定理气复胃口服液中木香烃内酯的含量 |
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| 引用本文： | 童荣生,孙世明,吴正中. 反相高效液相色谱法测定理气复胃口服液中木香烃内酯的含量[J]. 中国药房, 2006, 17(3): 211-212 |
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| 作者姓名： | 童荣生 孙世明 吴正中 |
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| 作者单位： | 四川省人民医院药剂科,成都市,610072 |
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| 摘 要： | 目的建立以反相高效液相色谱法测定理气复胃口服液中木香烃内酯含量的方法。方法色谱柱为Luna C18,流动相为甲醇-水(72∶28),流速为1.0ml/min,检测波长为225nm,灵敏度为0.001AUFS。结果木香烃内酯进样量在0.2μg~2.0μg范围内与峰面积积分值呈良好的线性关系(r=0.9996),平均加样回收率为98.4%(RSD=0.85%)。结论本方法简便、灵敏、准确、重现性好,可用于理气复胃口服液的质量控制。
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| 关 键 词： | 反相高效液相色谱法 理气复胃口服液 木香烃内酯 含量测定 |
| 文章编号： | 1001-0408(2006)03-0211-02 |
| 收稿时间： | 2005-03-11 |
| 修稿时间： | 2005-05-25 |
Content Determination of Costunolide in Liqifuwei Oral Liquid by RP-HPLC |
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| TONG Rongsheng,SUN Shiming,WU Zhengzhong. Content Determination of Costunolide in Liqifuwei Oral Liquid by RP-HPLC[J]. China Pharmacy, 2006, 17(3): 211-212 |
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| Authors: | TONG Rongsheng SUN Shiming WU Zhengzhong |
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| Abstract: | OBJECTIVE:To establish a RP-HPLC method for content determination of costunolide in Liqifuwei oral liquid.METHODS:The assay was performed on a Luna C 18 column by UV detector at the wavelength of225nm with methanol-water(72∶28)as the mobile phase at the flow rate of1.0ml/min.RESULTS:The amount of costunolide was linear with its area over the range from0.2μg～2.0μg(r=0.9996),the average recovery was98.4%(RSD=0.85%).CONCLUSION:The present method is convenient,sensitive and accurate with good reproducibility and can be used for the quality control of Liqifuwei oral liquid. |
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| Keywords: | RP - HPLC Liqifuwei oral liquid Costunolide Content determination |
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