| 追赶肥胖大鼠血清瘦素及游离瘦素受体水平的变化 |
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| 引用本文： | 于萍,文重远,李凝旭.追赶肥胖大鼠血清瘦素及游离瘦素受体水平的变化[J].武汉大学学报(医学版),2011,32(6):761-763,768. |
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| 作者姓名： | 于萍 文重远 李凝旭 |
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| 作者单位： | 武汉大学人民医院内分泌科 湖北武汉430060 |
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| 摘 要： | 目的:通过观察大鼠追赶肥胖过程中瘦素及游离瘦素受体水平变化，进一步揭示追赶肥胖发生机制。方法:5周龄Wistar雄性大鼠适应性喂养1周后随机分为对照组(NC)和追赶肥胖组(RN)，RN组予半量饮食喂养4周后开放饮食8周，NC组开放饮食12周。分别于实验第0，4，6，8，12周采集血液并剥离内脏脂肪，测内脏脂肪（以两侧肾...
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| 关 键 词： | 追赶肥胖 游离瘦素受体 瘦素 内脏脂肪 |
Changes of Serum Leptin and Soluble Leptin Receptor in Catch-up Fat Rats |
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| YU Ping,WEN Zhongyuan,LI Ningxu.Changes of Serum Leptin and Soluble Leptin Receptor in Catch-up Fat Rats[J].Medical Journal of Wuhan University,2011,32(6):761-763,768. |
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| Authors: | YU Ping WEN Zhongyuan LI Ningxu |
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| Institution: | YU Ping,WEN Zhongyuan,LI Ningxu Dept.of Endocrinology,Renmin Hospital of Wuhan University,Wuhan 430060,China |
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| Abstract: | Objective: To further reveal the mechanism of catch-up fat by observing the changes of leptin and soluble leptin receptor(sLR) in the process of catch-up fat in male rats.Methods: Five-week-old male Wistar rats were randomly divided into two groups: RN group(refeeding normal chow group after food restriction),which were given normal diet for another eight weeks after semistarvation for four weeks,and NC group(normal chow group),which were given free food for 12 weeks.The blood was collected and visceral fat... |
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| Keywords: | Catch-up Fat Soluble Leptin Receptor Leptin Visceral Fat |
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