| 血液CD3＋CD4＋／CD3＋CD8＋T细胞水平对肺部真菌感染的影响 |
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| 引用本文： | 齐天杰,阎锡新,张鲁涛.血液CD3＋CD4＋／CD3＋CD8＋T细胞水平对肺部真菌感染的影响[J].河北医药,2011,33(20):3045-3047. |
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| 作者姓名： | 齐天杰 阎锡新 张鲁涛 |
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| 作者单位： | 河北医科大学第二医院呼吸内科, 石家庄市,050000 |
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| 基金项目： | 河北省科学技术研究与发展支撑计划项目(编号:072761981); 河北省医学科学研究重点课题(编号:20100069) |
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| 摘 要： | 目的探讨血液CD3＋CD4＋／CD3＋CD8＋T淋巴细胞水平对非HIV感染患者发生侵袭性肺部真菌感染的影响。方法根据入选标准及诊治规范，入选IPFI组患者61例，非IPFI肺炎组患者47例及同期健康对照组体检者30例。收集记录上述患者的临床资料，观察3组病例CD3CD；T淋巴细胞百分比，CD3＋CD8＋T淋巴细胞百分比及CD3＋CD4＋／CD3＋CD8＋T淋巴细胞比值情况。结果白色念珠菌仍是最常见的致病真菌，占总检出菌株数的46．03％，同时本研究曲霉菌（30．16％）感染也占有相当高的比例。CD3＋CD4＋T淋巴细胞百分比及CD3＋CD4＋／CD3＋CD8＋T细胞比值水平，IPFI组较非IPFI肺炎组（t=5．910，P〈0．05；t=7．395，P〈0．05）及健康对照组（t=6．443，P〈0．05；t=7．428，P〈0．05）均明显下降。结论血液CD4＋／CD8＋T淋巴细胞水平测定有助于早期发现肺部真菌感染的发生。
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| 关 键 词： | 肺部真菌感染 细胞计 CD3＋CD4＋T淋巴细胞 CD3＋CD8＋T淋巴细胞 |
The effects of the ration of CD_3~+ CD_4~+/CD_3~+ CD_8~+ T cells on patients with pulmonary fungal infection |
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| QI Tianjie,YAN Xixin,ZHANG Lutao.The effects of the ration of CD_3~+ CD_4~+/CD_3~+ CD_8~+ T cells on patients with pulmonary fungal infection[J].Hebei Medical Journal,2011,33(20):3045-3047. |
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| Authors: | QI Tianjie YAN Xixin ZHANG Lutao |
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| Institution: | QI Tianjie,YAN Xixin,ZHANG Lutao.Department of Respiratory Medicine,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China |
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| Abstract: | Objective To investigate the effects of the ration of CD3+ CD4+/CD3+CD8+ T cells on the patients with pulmonary fungal infection,without HIV infection.Methods According to the inclusion criteria and the standard of diagnosis and treatment,61patients were enrolled into IPFI group,47 patients were enrolled into non-IPFI group and 30 healthy subjects were enrolled into normal control group.The clinical data of these patients were collected,and the percentages of CD3+ CD4+ T cells and CD3+ CD8+ T cells,and the ... |
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| Keywords: | pulmonary fungal infection cell count CD3 CD4 T cells CD3 CD8 T cells |
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